Alice Ting
Alice Ting
Professor of Genetics, of Biology and, by courtesy, of Chemistry
Molecular technologies for studying protein networks, mitochondria, brains & RNA
Appointments
Professor, Genetics
Professor, Biology
Professor (By courtesy), Chemistry
Member, Bio-X
Member, Maternal & Child Health Research Institute (MCHRI)
Faculty Fellow, Sarafan ChEM-H
Member, Stanford Cancer Institute
Member, Wu Tsai Neurosciences Institute
Other Appointments
Professor of Genetics, Biology, and by courtesy, Chemistry, Stanford University (2016 - Present)
Professor of Chemistry, MIT (2014 - 2016)
Associate Professor of Chemistry, MIT (2007 - 2014)
Assistant Professor of Chemistry, MIT (2002 - 2007)
Honors & Awards
Bruce Merrifield Distinguished Lecture, Rockefeller (2020)
NIH Director’s Transformative Research Award, NIH (2018)
Chan Zuckerberg Biohub Investigator, Chan Zuckerberg Biohub (2017)
Arthur C. Cope Scholar Award, American Chemical Society (2010)
NIH Director’s Pioneer Award, NIH (2008)
McKnight Technological Innovations in Neuroscience Award, McKnight Foundation (2005)
HHMI Collaborative Innovation Award, HHMI (2012)
NIH Director’s Transformative Research Award, NIH (2013)
Alexander M. Cruickshank Award Lecture, . (2018)
Prize for Creative Promise in Biomedical Science, Vilcek Foundation (2012)
Professional Education
Post-doc, University of California, San Diego, Biochemistry (with Roger Tsien) (2002)
Ph.D., University of California, Berkeley, Chemistry (with Peter Schultz) (2000)
A.B., Harvard University, Chemistry (research advisor E. J. Corey) (1996)
High school, Texas Academy of Math and Science (1992)
Featured Publications
Wang, W., Wildes, C. P., Pattarabanjird, T., Sanchez, M. I., Glober, G. F., Matthews, G. A., … Ting, A. Y. (2017). A light- and calcium-gated transcription factor for imaging and manipulating activated neurons. Nature Biotechnology.
Kim, C. K., Sanchez, M. I., Hoerbelt, P., Fenno, L. E., Malenka, R. C., Deisseroth, K., & Ting, A. Y. (2020). A Molecular Calcium Integrator Reveals a Striatal Cell Type Driving Aversion. Cell.
Martell, J. D., Yamagata, M., Deerinck, T. J., Phan, S., Kwa, C. G., Ellisman, M. H., … Ting, A. Y. (2016). A split horseradish peroxidase for the detection of intercellular protein-protein interactions and sensitive visualization of synapses. Nature Biotechnology, 34(7), 774–80.
Coukos, R. W., Yao, D., Sanchez, M. L., Strand, E. T., Olive, M. E., Udeshi, N. D., … Ting, A. Y. (2021). An engineered transcriptional reporter of protein localization identifies regulators of mitochondrial and ER membrane protein trafficking in high-throughput CRISPRi screens. ELife, 10.
Fazal, F. M., Han, S., Parker, K. R., Kaewsapsak, P., Xu, J., Boettiger, A. N., … Ting, A. Y. (2019). Atlas of Subcellular RNA Localization Revealed by APEX-Seq. Cell.
Liu, D. S., Nivon, L. G., Richter, F., Goldman, P. J., Deerinck, T. J., Yao, J. Z., … Ting, A. Y. (2014). Computational design of a red fluorophore ligase for site-specific protein labeling in living cells. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 111(43), E4551–E4559.
Lam, S. S., Martell, J. D., Kamer, K. J., Deerinck, T. J., Ellisman, M. H., Mootha, V. K., & Ting, A. Y. (2015). Directed evolution of APEX2 for electron microscopy and proximity labeling. NATURE METHODS, 12(1), 51–54.
Branon, T. C., Bosch, J. A., Sanchez, A. D., Udeshi, N. D., Svinkina, T., Carr, S. A., … Ting, A. Y. (2018). Efficient proximity labeling in living cells and organisms with TurboID. NATURE BIOTECHNOLOGY, 36(9), 880-+.
Martell, J. D., Deerinck, T. J., Sancak, Y., Poulos, T. L., Mootha, V. K., Sosinsky, G. E., … Ting, A. Y. (2012). Engineered ascorbate peroxidase as a genetically encoded reporter for electron microscopy. NATURE BIOTECHNOLOGY, 30(11), 1143-?
Loh, K. H., Stawski, P. S., Draycott, A. S., Udeshi, N. D., Lehrman, E. K., Wilton, D. K., … Ting, A. Y. (2016). Proteomic Analysis of Unbounded Cellular Compartments: Synaptic Clefts. Cell, 166(5), 1295–1307 e21.
