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GSK is seeking a proactive chemist to join Drug Substance Development at our US R&D Hub located in Upper Providence, PA. Our Drug Substance Development group supports the small molecule portfolio in GSK Pharma R&D with an inter-disciplinary team of process chemists, chemical engineers, materials scientists, and synthetic biochemists by developing the synthetic routes and associated manufacturing processes that turn those molecules into medicines. Through our network of 86 manufacturing sites, each year we produce nearly 4 billion packs of medicine, and we are committed to widening access to our products so that more people may benefit. A successful applicant will have an excellent practical and theoretical understanding of synthetic organic chemistry or a relevant technology and can design and execute high quality, thoughtful experimentation, while making significant contributions both independently and as a member of a team. 

As a member of Drug Substance Development, you will use your chemistry knowledge and expertise to develop new chemistry routes for primary manufacture and contribute to the development and deployment of state-of-the-art processes and technologies to enable the delivery of our medicines.  This is a highly practical role where you will be working in the R&D laboratories to generate new synthetic routes and process understanding that underpins the successful scale-up and commercial industrialization of GSK’s future manufacturing processes. Your focus will be to combine the information generated in laboratory studies with your strong knowledge of synthetic organic chemistry to develop sustainable pharmaceutical manufacturing routes and processes. 

Why You

Success in GSK thrives on strong interpersonal skills and practical chemistry skills combined with a curious, inquisitive nature and a passion for science. You are equally passionate about developing yourself, developing new scientific methodologies, pushing the limits of innovation, and learning something new every day. You are an excellent team player, able to work with others either in the lab or in the office as well as within cross-functional teams. You are independent and able to plan and execute your own workload and deliver results.  Your science is conducted with integrity, safety, and the highest standards.  You pride yourself in your chemistry and enjoy science as much as we do.

When submitting your CV/Resume please also include a Research Statement.

This role will provide YOU the opportunity to lead key activities to progress YOUR career. These responsibilities include some of the following:

• Designing and performing experiments in a laboratory setting to meet project timelines and objectives. 
• Thinking creatively to generate new ideas for new synthetic routes and simplifying process problems. 
• Ensuring that experimental work is communicated effectively at internal R&D meetings. 
• Participating in technology transfer activities as appropriate to our manufacturing partners Global Supply Chain (GSC), other parts of R&D, and partner Contract Manufacturing Organizations (CMOs). 
• Authoring or contributing to regulatory submissions, patents, scientific papers and other internal documentation relevant to the role. 
• Complying with applicable Data Integrity, Quality, cGMP and regulatory requirements in all aspects of work. 
• Staying up to date with the latest advancements in chemistry and technologies aligned to the group remit and evaluate their potential applications for process development of GSK’s portfolio.

Basic Qualifications:

We are looking for professionals with these required skills to achieve our goals:

• PhD in Organic Chemistry or equivalent field with 0+ years' experience OR Master's Degree in Organic Chemistry or equivalent field with 5+ years' experience

Preferred Qualifications:

If you have the following characteristics, it would be a plus:

• Expertise in total synthesis and/or synthetic methodology development
• Experience in Design of Experiments (DoE)  
• Experience in implementation of basic kinetic characterization of organic reactions
• Highly organized with strong attention to detail and a focus on quality results
• Knowledge of regulatory requirements and drug development process
• Scientific record demonstrating excellence in chemistry (e.g., publications, patents, or presentations) 
• Experience in independent planning and execution of experiments 
• Experience in independent interpretation of data from experiments and using it to make meaningful conclusions/decisions regarding the direction of future experimentation.
• Project management experience
• Experience analyzing data

Location: USA - Pennsylvania - Upper Providence

Job requisition ID: 418731

To Apply: Click here

Deadline: Applications accepted on a rolling basis till April 30th