Total Synthesis and Biological Evaluation of Natural and Designed Molecules of Biological and Medical Importance
About the Seminar
This lecture will cover a number of topics dealing with total synthesis, molecular design and biological testing of complex molecules relevant to biology and medicine, including the antibiotics viridicatumtoxin B and CJ-16,264 and antitumor agents N14-desacetoxytubulysin H, (delta)12-prostaglandin J3, shishijimicin A, uncialamycin, and trioxacarcin C.
About the Speaker
For his scientific work, Professor Nicolaou has received numerous awards and honors. He is the author or co-author of more than 760 scientific articles, reviews, and book chapters, 67 patents, and 5 books, including the popular Classics in Total Synthesis co-authored with his student E.J. Sorensen (1996, VCH), Classics in Total Synthesis II co-authored with his student S.A. Snyder (2003, Wiley-VCH),Classics in Total Synthesis III co-authored with his student J.S. Chen (2011, Wiley-VCH), and Molecules that Changed the World, co-authored with his research associate T. Montagnon (2008, Wiley-VCH). His dedication to chemical education is evidenced by his training of hundreds of graduate students and postdoctoral fellows.