Professor Abigail G. Doyle, Princeton University

"New Methods and Mechanisms in Asymmetric Catalysis"

About the Seminar

Research in the Doyle lab takes place at the interface between the fields of organic synthesis, organometallic chemistry, and physical organic chemistry. We are involved in designing synthetic strategies that enable efficient and selective preparation of complex molecules and biologically privileged structural motifs. To achieve these goals, we harness the activity of inexpensive and abundant transition metal catalysts to achieve novel bond-forming processes. In the past, we have pursued two areas within this program: (1) the invention of new catalytic reaction methods for the synthesis of fluorinated compounds using nucleophilic fluorine sources; and (2) the development of transition metal-catalyzed C(sp3)-C bond-forming reactions with electrophiles that possess abundant but unconventional leaving groups.

About the Speaker

Abigail G. Doyle was born in Princeton, NJ in 1980. She obtained her A.B. and A.M. degrees summa cum laude in Chemistry and Chemical Biology from Harvard University in 2002. After spending the subsequent year at Stanford University working with Professor Justin Du Bois, she joined the laboratory of Professor Eric Jacobsen at Harvard University for her doctoral studies, which were centered in the area of enantioselective catalysis. Abby began as an Assistant Professor in the Department of Chemistry at Princeton University in 2008. In 2013, she was promoted to Associate Professor. Research in the Doyle group is centered in the area of catalysis, with specific interests in the development of novel nickel-catalyzed cross-coupling reactions and the identification of new reagents and strategies for nucleophilic (radio)fluorination.