Organic Chemistry Seminar: Professor Amanda L. Garner, University of Michigan

About the Seminar

Enabling Technologies for Revealing Druggable Paths in RNA Biology

RNAs are invariably bound to and often modified by RNA-binding proteins (RBPs), which regulate many aspects of coding and non-coding RNA biology. Disruption of this network of RNA-protein interactions (RPIs) has been implicated in a number of human diseases and targeting RPIs has arisen as a new frontier in RNA-targeted drug discovery. This talk will highlight newly developed technologies by the Garner laboratory for validating and screening RPIs to enable RBP-targeted drug discovery and reveal new druggable paths in RNA biology.

Host: Eric Kool